Hepatitis C Therapy: Depression


Tell your health care provider immediately about any suicidal thoughts or thoughts about hurting others.
Some people experience depression while on therapy for hepatitis C. Depression is very serious, not just a feeling of being "down" or "the blues." You may not notice a change in your own personality, but members of your family, your friends, or your caregiver might.

Signs of Clinical Depression
Fatigue that doesn't improve with rest
Sleeping much more or much less than usual
Continual, long-lasting feelings of sadness—anxious, tearful, irritable, or sad most of the day
Hopelessness, despair
Extreme mood swings
Loss of interest in things you used to love to do such as eating, socializing, sex, etc.
Feelings of guilt or worthlessness
Problems thinking, concentrating, making decisions
Eating more or less than usual or having lost or gained weight
Feeling like you're talking or walking in slow motion
Having thoughts about death, giving up, wanting to die

It's common to briefly experience mood swings, confusion, anxiety, and sadness during therapy. But a person who is depressed might not realize it. If your spouse, coach, or caregiver suggests that you might be "depressed," take this one seriously. You should contact your health care provider immediately, and follow his or her recommendations.

Speak to Your Doctor
Tell your health care provider about any time you may have had depression in the past—mental status changes can be complicated by underlying depression and anxiety and fear related to anticipation of the effects of therapy.
Review with your doctor all medications you are taking, as they may be causing your depression.
Patients with a history of alcohol or drug use may experience a relapse. Tell your health care provider of any history of alcohol or drug use—monitoring and early intervention are important.
Be aware of any mood changes, suicidal thoughts, or thoughts about hurting others and tell your family members and health care provider immediately.

Tips for Managing Depression
In some cases, depression may need to be managed with an antidepressant or short-acting anti-anxiety agent. Medication would be prescribed by your doctor.
Try mild-to-moderate exercise. Be aware that prolonged bed rest and too much inactivity is not good for you, either physically or psychologically. Talk to your doctor about an exercise program that's right for you.
Try to be aware of the things that depress you and avoid them if you can.
Consider support groups.
If you're afraid of a group, find yourself a personal therapist (psychiatrist, psychologist, clergy).
Get enough rest. If you feel tired and depressed, take a nap.
Take a walk in the park or on the sidewalk in front of your home.
Increase your fluid intake, but do not drink alcohol or caffeinated beverages.
If you are irritable, confused, or can't concentrate as well as you used to, take things slowly. If your memory is unreliable, make lists.
Remember there is an end in sight—your treatment will not go on forever.

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